Effects of Natamycin on Growth Performance, Serum Biochemical Parameters and Antioxidant Capacity in Broiler Chickens

A total of 360 broilers were fed with basal diets (CON group), basal diets supplemented with 10 or 50 mg/kg natamycin (T1 or T2 group) for 42d, respectively. The results showed that alkaline phosphatase in T2 group was significantly decreased at 21d, blood urea nitrogen and alanine aminotransferase were significantly increased compared to CON group at 42d in broilers. Serum globulin content (21d) and total protein content (42d) were lower in T2 group than that of CON group. Serum total antioxidant capacity was higher and malondialdehyde content was lower in T1 group than that of CON group at 21d. Serum glutathione peroxidase enzyme activity was significantly increased in T1 group compared to CON group at 42d. Malondialdehyde content of liver in T1 group was lower than that of CON group. These results suggested that dietary supplementation of 10 mg/kg natamycin had a positive influence in broilers.