Spontaneous Gamma Eeg Activity And Aging In Schizophrenia

Spontaneous gamma (SG; 30-100 Hz) activity has been related to cortical excitation/inhibition balance. We previously reported that SG power was increased in individuals with schizophrenia (SZ) compared to healthy controls (HC) during auditory steady-state stimulation, consistent with evidence of increased cortical excitability in schizophrenia. Increased spontaneous EEG activity has also been reported in healthy aging. As SZ is associated with accelerated neuroanatomical aging, here we investigated whether SG power in SZ increased with age to a greater degree than in HC.