Unique Pharmacology And Clinical Evidence Supporting The Antidepressant Therapeutic Potential Of Lumateperone
BIOLOGICAL PSYCHIATRY(2018)
摘要
Lumateperone (ITI-007) is a first-in-class investigational agent which simultaneously modulates serotonin, dopamine, and glutamate neurotransmission, currently in clinical development for schizophrenia, bipolar depression and agitation associated with dementia
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关键词
Rapid Antidepressant, mTOR, Glutamate Receptors, Dopamine D1 Receptors, Dopamine D2 Receptors
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