Plasma Interleukin 1 Beta Positively Correlates With Anxiety Scores In Youths With Bipolar Disorder
BIOLOGICAL PSYCHIATRY(2018)
Abstract
Bipolar Spectrum Disorders (BSD) and Anxiety Disorders are highly comorbid. Furthermore, school avoidance behavior can be a presenting symptom in youths with underlying anxiety. Immune dysfunction has been implicated in the pathophysiology of bipolar disorder but the role of immune markers such a proinflammatory cytokines in youths with bipolar disorder has not been adequately studied. We aimed to examine the association of the pro-inflammatory cytokine, IL-1β with anxiety symptoms and school avoidance behavior in youths with BSD.
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Key words
Anxiety, Mood Disorders, Bipolar Disorder, Metabolomics, Biomarkers
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