S2-4. Neuromodulative treatments for spasticity

Intractable and severe spasticity after CNS disturbance has the ability to impact on the quality of life (QOL), function and care of the patients. Where medical and physical treatments have proved insufficient, a surgical approach may be pursued. Irrespective of the underlying pathology, intrathecal baclofen (ITB) will reduce spasticity in a controllable and reversible fashion. Owing to the potential for complications of ITB, careful selection and preparation are required to produce satisfactory results. And ITB therapy can greatly improve activities of daily living and QOL, and this treatment is attracting attention as a neuromodulatory therapy that also affects metabolic and respiratory functions and even state of consciousness. We here report the surgical methods and therapeutic outcomes for our patients who underwent ITB therapy for spastic patients in our hospital, together with an investigation of the effects on metabolic and respiratory functions. We want to present the most up-to-date information about ITB therapy.