Identification of Leukocyte Subpopulations as Potential Biomarkers of Long-term Survival With Normal Allograft Function After Lung Transplantation

Long-term survival after lung transplantation (LT) is limited by the development of chronic lung allograph dysfunction (CLAD). Despite this fact, a small number of lung transplant recipients are long-term survivors with a good allograft function (LTS). A study of this particular population could be a first step to search for transplant tolerance biomarkers that can lead to the reduction of immunosuppressive drugs in treatment plans and improve personalized medicine. The objective of this study was to identify leukocyte subpopulations as potential tolerance biomarkers in LTS after lung transplantation.