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IL1RN Genotype and Infection Risk in Heart Recipients

I. Ezzahouri, D. Hernandez, C. Rodriguez-Sainz, L. Valor, E. Sarmiento, E. Fernandez-Cruz, J. Carbone

The Journal of Heart and Lung Transplantation（2018）

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Abstract
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. Previous epidemiological studies have presented evidence regarding associations between IL1RN polymorphisms and sepsis susceptibility. In the present study the potential role of IL-1RN genotypes was evaluated as a potential risk factor of severe infection in heart recipients.
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Key words
infection risk,heart
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