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Epicardial Infarct Repair with a Novel Biologic Extracellular Matrix Improves Infarct Healing: Preclinical Validation

Holly E. Mewhort,Jeannine D. Turnbull,Jacqueline A. Flewitt, H. C. Meijndert,David G. Guzzardi,Daniyil A. Svystonyuk, Christina Y. Yang,Brodie D. Lipon,Daniel S. Park,Paul W. Fedak

Circulation（2014）

Cited 23|Views9
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Abstract
BACKGROUND: Despite successful revascularization after MI, the extracellular matrix (ECM) continues to remodel resulting in cardiac fibrosis, LV dilatation and heart failure. We hypothesized that a...
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Key words
Extracellular matrix,Experimental heart failure,Remodeling,Tissue engineering,Fibrosis
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