Interferon alpha: A rare cause of persistent pulmonary hypertension of newborn

Medical Journal Armed Forces India(2020)

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Abstract
Implant restorations are considered an ideal treatment option for replacement of missing teeth in partially edentulous patients. Abutment screw loosening is one of the frequently observed technical complications of implant-supported prosthesis. This study aimed to determine the prevalence and factors associated with the abutment screw loosening in cement-retained single-implant crowns.Enrolment criteria included partially edentulous patients who have been rehabilitated with one or more cement-retained single-implant crowns with minimum postcementation period of 1 year. They were recalled and evaluated for the presence or absence of screw loosening both clinically and radiographically. They were further evaluated for the presence or absence of factors associated with screw loosening such as parafunctional habits, wider occlusal table, steep cuspal inclines, non-axial loading and cantilevering of the pontic.Twenty-six cement-retained single-implant crowns out of 280 showed screw loosening, making the overall prevalence rate of 10.77%. Among the factors evaluated, parafunctional habits were associated with three cases, wider occlusal table in four, steep cuspal inclines in three, non-axial loading in nine and cantilevering of the pontic in three cases. Exact reasons could not be ascertained in four cases.Abutment screw loosening seems to be a significant prosthetic complication of cement-retained single-implant crowns. Factors evaluated significantly affect the functional durability of the prosthesis. These factors should be considered while restoring to enhance the longevity of such restorations.
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Key words
Persistent pulmonary hypertension,Newborn,Interferon alpha
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