Visual detection of Pb 2+ using strip biosensor based on PS2M aptamer and sensitivity enhancement probe

Hai-Bo Wang,Li-Hong Ma,Bi-Yun Fang,Fang Tan,Yuan-Cheng Cao,Yuan-Di Zhao,Xue-Bin Hu

Sensors and Actuators B: Chemical（2018）

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摘要

•AuNP-DNA polymer was pre-prepared as sensitivity enhancement probe (SEP) to improve sensitivity of strip for the first time.•Compared with the strip biosensor without SEP, the sensitivity of strip with SEP was increased by 40 times.•The strip biosensor enables visual detection of Pb2+ within 20 min with 2.5 nM LOD.

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关键词

PS2M aptamer,G-Quadruplex structure,Sensitivity enhancement probe,Strip biosensor,Lead ion,Au nanoparticle

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