Human and animal evidence of potential transgenerational inheritance of health effects: An evidence map and state-of-the-science evaluation

•Transgenerational effects are reported in both humans and animals.•There are few bodies of evidence evaluating the same exposure and similar outcomes.•Risk of bias assessment identified issues in study design, conduct, and reporting.•Heterogeneity, bias limit bodies of evidence assessing transgenerational effects.•Target future data to address inconsistencies and risk of bias issues.