THE RECEPTOR FOR COMPLEMENT COMPONENT C3A MEDIATES PROTECTION FROM THE DEVELOPMENT OF ATHEROSCLEROSIS IN APOLIPOPROTEIN E DEFICIENT (APOE-/-) MICE

Linlin Wei,Ning Ma,YaFeng Gao,Jiaxing Wang,Liang Bai,Daxin Chen,Ke Li

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2018）

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摘要

The complement system is a key component of the innate immunity playing important roles in immune surveillance and regulating immune homeostasis. Previous studies have suggested that complement activation generates C5a and its receptor interaction significantly contribute to the pathogenesis of

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apolipoprotein,atherosclerosis,receptor

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