Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms

Tariq I. Mughal,Jason Gotlib,Ruben A. Mesa,Steffen Koschmieder,H. Jean Khoury,Jorge Cortes,Tiziano Barbui,Rüdiger Hehlmann,Michael J. Mauro,Susanne Saussele,Jerald P. Radich,Richard A. Van Etten,Giuseppe Saglio,Srdnan Verstovek,Robert Peter Gale,Omar Abdel-Wahab

Leukemia Research（2018）

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摘要

•Importance of treatment-free remission for patients with CML on TKIs.•Genomics guiding clinical management of patients with MPNs.•Targeted therapy for patients with systemic mastocytosis.•Emerging treatments for MPNs.

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关键词

CML,MPN,TFR,Mastocytosis,CALR,Cardiotoxicity,JAK2 inhibitors

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