BEDSIDE TESTING OF CYP2C19 GENOTYPE TO GUIDE ANTIPLATELET THERAPY: IMPLEMENTATION IN THE CATHETERIZATION LABORATORY

Paul A. Gurbel,Rachel Bell,Kevin P. Bliden,Shahram Yazdani,Hamid Taheri, Marjaneh Akbari,Behnam Tehrani,Heather Russell,Ramaswamy Iyer,Udaya S. Tantry

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2018）

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摘要

Although FDA recommended pharmacogenetic testing and alternative antiplatelet agents in CYP2C19 loss-of-function(LoF) allele carriers in patients treated with clopidogrel, implementation in practice has been minimal. Appropriate P2Y12 receptor antagonist therapy following PCI based on bedside

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cyp2c19 genotype,guide antiplatelet therapy

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