The impact of change in prophylactic antibiotics on infectious complications after radical cystectomy with orthotopic neobladder

CONCLUSIONS: In patients undergoing ureteroscopy for urolithiasis, who received alternative prophylaxis according to the AUA Best Practice Statement, infectious complications were reported in 15.4% of cases.This incidence is surprisingly high and may be reflective of a tertiary care experience with higher-risk patients.However, it may also suggest that alternative prophylaxis, which is largely generalized from other surgical experiences and our knowledge of genitourinary flora may require more vigorous validation and be tailored to account for local antibiograms.