TOPAS Monte Carlo model of MD anderson scanning proton beam for simulation studies in proton therapy

A Monte Carlo model of the MD Anderson Cancer Center clinical scanning proton beam is created using the TOol for PArticle Simulations (TOPAS). This model is based on the commissioning data of integrated depth dose curves (IDDs) and lateral profiles of single proton spots. The mean range errors on the Bragg Peak (BP) for all energies are <0.1% of the range (mu = -0.01%, sigma = 0.05%). As an example of a possible application of this model, a quality assurance phantom measurement is simulated. The model can be used in further simulation studies of quality assurance, intensity modulated proton therapy, or MRI-guided proton therapy.