Impact Of Left Atrial Size And Function On Exercise Hemodynamics In Patients With Heart Failure With Mid-Range And Preserved Ejection Fraction

Emma Gard,Shane Nanayakkara,Sanjiv Jayendra Shah,Barry Borlaug,Frank Silvestry,Thomas Hanff,Scott L. Hummel,Sheldon Litwin, Mark Petrie,Jan Komtebedde, David Kaye

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2018）

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摘要

The pathophysiologic hallmark of heart failure with preserved ejection fraction (HFpEF) and mid-range ejection fraction (HFmrEF) is elevated left ventricular filling pressure. Chronic elevations in filling pressures lead to left atrial (LA) enlargement, which may impair LA function and further

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