FROPOFOL PREVENTS DISEASE PROGRESSION IN HYPERTROPHIC CARDIOMYOPATHY

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY(2018)

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摘要
Increased contractility by the myofilaments themselves is recognized as a crucial factor in the pathogenesis of hypertrophic cardiomyopathy (HCM). In this study, we test the hypothesis that fropofol (a propofol derivative with no anesthetic activity), is a direct myofilament depressing agent that
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disease
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