Effectiveness Of Selective Plasma Exchange Therapy (Sepe) In Patients With Myasthenia Gravis

Background: Selective plasma exchange (SePE) is a new modality of plasmapheresis using a membrane plasma separator (EVACURE EC-4A10Ⓡ; Kawasumi Laboratories Inc., Tokyo, Japan) with smaller than ordinary pores. SePE can remove IgG and cytokines while retaining high molecular weight substances such as fibrinogen and factor 13 which are coagulation factor components.