Heteroduplex Oligonucleotide As A Platform Technology To Modulate Blood-Brain Barrier Function In Vivo
JOURNAL OF THE NEUROLOGICAL SCIENCES(2017)
Abstract
Background: The blood-brain barrier (BBB) is a pathologic site in many neurological disorders such as multiple sclerosis, brain ischemia, and neurodegenerative diseases. Modulation of BBB function by an oligonucleotide-based gene silencing would be beneficial for a variety of basic and clinical studies.
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Key words
vivo,blood-brain
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