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Evaluation Of Serum Creatine Kinase And Uric Acid In Bulbar-Onset And Limb-Onset Amyotrophic Lateral Sclerosis

Takuto Hideyama,Tomonari Seki,A. Mitsutake,Tatsuya Sato, K. Junko,Risa Maekawa,Yasushi Shiio

JOURNAL OF THE NEUROLOGICAL SCIENCES（2017）

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Abstract
Background: Amyotrophic lateral sclerosis (ALS) is a common adult-onset neurodegenerative disease of unknown etiology and there is no useful diagnostic biomarker. Several reports indicated the levels of the creatine kinase (CK) and uric acid (UA) seem to be an independent variables of progression in ALS.
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Key words
amyotrophic lateral sclerosis,serum creatine kinase,uric acid,bulbar-onset,limb-onset
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