Dynamic Biomolecule Sensing Bead Array Held by Optical Tweezers

Christopher N Lafratta,Manuel A Palacios,Aaron F Phillips,David R Walt,Mael Manesse

Optics in the Life Sciences (2011), paper OTTuC4（2011）

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摘要

We have developed a platform using optical tweezers to create dynamic arrays of functionalized microbeads in microfluidic channels. The array is then exposed to analyte signaling molecules and washes, and interrogated using fluorescence microscopy.

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