Polysaccharide isolated from Chinese jujube fruit (Zizyphus jujuba cv. Junzao) exerts anti-inflammatory effects through MAPK signaling
Journal of Functional Foods(2018)
Abstract
•A pectic polysaccharide was isolated from Zizyphus jujuba cv. Junzao.•The structure of ZJP was characterized by chemical analysis, FT-IR, NMR and GPC-MALLS.•ZJP showed strong anti-inflammatory activity on RAW 264.7 cells.•ZJP could be used to treat inflammatory disease or in health products.
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Key words
CCK8,COX-2,ERK1/2,IFN-γ,iNOS,IL-17,JNK,LPS,MAPKs,NO,PGE2,PMP,TLR4,TNF-α,NSAIDs
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