Basic C-peptidemia and Diabetic Patients Classification

Diabetes is a real public health problem in the world. In Africa in general and in Cote du0027Ivoire in particular, the management of diabetes is complicated by socio-economic difficulties. After the diagnosis of diabetes, its typing is carried out on the basis of clinical criteria. With the discovery of many subgroups of diabetes especially in Africa, the classification of diabetes is made difficult. This difficulty may raise questions about the adequacy of the therapeutic treatment of patients. The purpose of this study was to study mainly the contribution of basal C-peptidemia in the typing of diabetic subjects. The material concerned a population of 220 diabetics who carried out their peptide C assay and monitored at the Yopougon-ABIDJAN University and Hospital Center. Basal C-Peptidemia was assayed by competitive radio-immunoassay using the kit CIS –BIO Shering. The results revealed that the classification based on clinical signs was improved after the C-peptide assay. Indeed, after C-peptidemia, type 1 diabetics with low C-peptidemia (u003c0.5 ng/ml) and type 2 diabetics with normal C-peptidemia (0.5 ng/ml to 3 ng/ml). In conclusion, the determination of peptide C appears as an undeniable tool for better classification of diabetic patients. The results of C-peptidemia would direct the practitioner towards a more adequate treatment in the patients studied.