Aptamer-functionalized DNA nanosphere as a stimuli-responsive nanocarrier

Supattra Chaithongyot,Nusara Chomanee,Komgrid Charngkaew,Anuttara Udomprasert,Thaned Kangsamaksin

Materials Letters（2018）

引用 11|浏览6

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摘要

•A MUC1-responsive DNA nanosphere has been constructed via the scaffolded DNA origami technique.•The structure undergoes conformational change to the open structure in response to MUC1.•The DNA nanostructure possesses cargo loading ability.

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关键词

DNA origami,DNA nanosphere,MUC1 aptamer,Targeted drug delivery system

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