Chemical constituents from Bauhinia acuruana and their cytotoxicity

Phytochemical investigation of Bauhinia acuruana Moric., Fabaceae, resulted in the isolation of sixteen constituents, including two new compounds 2′-hydroxy-2,3,5-trimethoxybibenzyl ( 1 ), (2R,3S)-2-(3,4′-dihydroxyphenyl)-5-methoxy-6-methylchroman-3,7-diol ( 2 ), together with fourteen known ones ( 3–16 ). The structures of the compounds were established by spectroscopic analysis including HR-ESIMS, 1D and 2D NMR data, followed by comparison with previously reported data from the literature. Compounds 1, 2, 6, 7, 8 and 9 were evaluated for their cytotoxicity, which turned out to be marginal in a panel of six human cancer cell lines.