Extending the platinum-free Interval: The impact of omitting 2nd line platinum chemotherapy in intermediate platinum-sensitive ovarian cancer

L.E. Dockery,A.R. Rubenstein,K. Ding,S.G. Mashburn,W.C. Burkett, A. Montgomery,D.W. Doo,R.C. Arend,K.N. Moore,C.C. Gunderson

GYNECOLOGIC ONCOLOGY（2019）

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摘要

•Non-platinum chemo or targeted therapy to prolong PFI in platinum intermediate recurrent ovarian cancer worsens survival.•This confirms existing prospective data from the MITO-8 study.•Even with targeted therapies, attempts to artificially prolong the PFI are not likely beneficial.

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关键词

Ovarian cancer,Platinum sensitivity,Chemotherapy,PFI,MITO-8

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