Analysis of Long-Term Complication on Patients with Obstructive Sleep Apnea Who Treated Mandibular Advancement Device

Background and ObjectivesZZRecently, mandibular advancement device (MAD) has been used widely used for the treatment of obstructive sleep apnea (OSA) because it can effectively reduce the collapsibility of upper airway during sleep.Although MAD is widely prescribed by otorhinolaryngologists, several studies described its complications arising from the anterior placement of the mandible with long-term use.However, there is still a lack of studies on longterm complications in Korean patients.Subjects and MethodZZRetrospectively, we included a total of 57 OSA patients in the study.In this study, all enrolled OSA patients had used MAD over two years with more than 4 hours/ day.Dental consulting and cephalometric analysis were conducted to identify the change of dental and skeletal findings at two different times (baseline and after 2 year).ResultsZZThe dental findings showed that the overbite and overjet were significantly decreased.Additionally, the proclination of the lower incisors were increased significantly, whereas there was no significant change on the retroclination of the upper incisors.Three patients showed a change of malocclusion type.On the analysis of skeletal findings, we found a significant increase in the sella turcica central point-nasion-supramental point angle and a decrease in the subspinal point-nasion-supramental point angle.Moreover, the anterior lower facial height and anterior facial height were significant increased.ConclusionZZConsistent with Western studies, our findings suggest that the long-term use of MAD could induce changes in dental and skeletal morphologies in Korean OSA patients.Therefore, clinicians should thoroughly evaluate potential changes in dental and skeletal morphologies when they prescribe MAD to patients with OSA.