5,10,15,20-Tetrakis (4-carboxyphenyl) porphin-conjugated poly(l-lactic) acid/polyethylene oxide nanofiber membranes for photodynamic therapy

Fang Ma,Chun-Wang Yuan,Xiao-Xue Ren,Chang-Jiang You,Jian-Hua Cao,Da-Yong Wu

Journal of Photochemistry and Photobiology A: Chemistry（2018）

引用 53|浏览8

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摘要

•We prepared a PLLA/PEO nanofiber membrane containing TCPP to treat cancer cells.•PEO improved the hydrophilicity of the nanofibers.•TCPP produced 1O2 at light irradiation (532nm).•The nanofiber membranes were cytotoxic in cancer cells under light irradiation.

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关键词

Electrospun nanofiber,Drug carrier,Singlet oxygen,Photodynamic therapy,HeLa cells

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