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Genomic Landscape of Mixed Phenotype Acute Leukemia (MPAL)

Kiyomi Morita,Feng Wang, Keyur P. Patel,Carlos E. Bueso-Ramos,Abdallah Abou Zhar,Curtis Gumbs,Latasha Little,Samantha Tippen,Rebecca Thornton,Marcus Coyle,Jianhua Zhang,Xingzhi Song,Marisela Mendoza,Chang-jiun Wu,Steven M. Kornblau,Courtney D. DiNardo,Farhad Ravandi,Guillermo Garcia-Manero,Elias Jabbour,Michael Andreeff,Hagop M. Kantarjian,Jorge Cortes,Marina Konopleva,Andrew Futreal,Koichi Takahashi

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA（2017）

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Abstract
Mixed phenotype acute leukemia (MPAL) is a rare subgroup of acute leukemia characterized by blasts that show immunophenotypes of both myeloid and lymphoid lineages. It poses significant diagnostic and therapeutic challenges in clinic, yet genetic basis of MPAL is not well understood.
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mixed phenotype acute leukemia,genomic landscape,mpal
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