Performance of the Karius Plasma Next Generation Sequencing Test in Determining the Etiologic Diagnosis of Febrile Neutropenia: Results from a Pilot Study

Esther Benamu,Kiran Gajurel,Jill N. Anderson,Hon Seng,Desiree Hollemon,David K. Hong, Timothy A Blawkamp,Mickey Kertesz,Heather D. Ishak,Paul L. Bollyky,Bruno C. Medeiros,Steven Coutre,Jose G. Montoya,Stan Deresinski

Open Forum Infectious Diseases（2017）

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摘要

Background Blood cultures (BC) fail to detect a pathogen in most patients with neutropenic fever (NF). We examined the performance of the Karius next generation sequencing plasma test (plasma NGS) compared with that of BC in chemotherapy-induced NF.

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