Electrochemical sensing of estradiol benzoate using hydroxyapatite with three-dimensional channel frameworks

Ubiquitous estradiol benzoate (17 beta-estradiol-3-benzoate) in the environment and daily life has become a hot issue in society since it has been proven to be closely associated with metastatic tumour formation. In the current work, hydroxyapatite with three-dimensional channel frameworks has been successfully demonstrated to be highly sensitive for the electroanalytical sensing of this pollutant, with a detection limit of 24.4 ng L-1 (0.065 nM), attributed to the enhanced electron transport capabilities and three-dimensional structure of the hydroxyapatite structure/surface.