CO-EXPRESSED TRANSCRIPTOME ANALYSES REVEAL CONSISTENT BIOLOGICAL PATHWAYS FOR MANIC EPISODE

Bipolar disorder (BD) is a highly heritable psychiatric disorder with recurrent episodes of depression and mania. Despite progress made for identifying genetic variants for BD, limited studies focus on its episodic feature in nature. In the current study, we aimed to investigate the mechanisms underlying manic episodes at a genome-wide level to identify potential molecular targets, in particular the gene/transcript expression patterns.