Study on Three Typical Chinese Traditional Patent Medicines Using Temperature-Dependent X-ray Diffraction Technique

The temperature-dependent XRD technique was used to study three typical Chinese traditional patent medicines (CTPMs)—Suxiao Jiuxin pills (SJP), Zhenqi Fuzheng granules (ZFG), and Shenyang Hongyao tablets (SHT). The results showed that this technique can convincingly evaluate crystalline structure, sublimation, melting, temperature stability of some molecular crystals such as the pharmaceutical constituent (borneol) and base (PEG) in SJP, edulcorant (sucrose) in ZFG, and inorganic diluents (calcium sulfate) in SHT. The temperature-dependent XRD technique can be qualified for quality control of these CTPMs