Genetic and epigenetic heterogeneity and the impact on cancer relapse

Ciaran Hassan,Ebrahim Afshinnekoo,Sheng Li,Shixiu Wu,Christopher E. Mason

Experimental Hematology（2017）

引用 29|浏览5

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摘要

•Genetic and epigenetic evolution can follow distinct and independent trajectories.•New epigenetic technologies improve diagnostic accuracy and clinical application.•Epigenetic CRISPR editing can reprogram the aberrant sites of DNA methylation.

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