A jasmonic acid derivative improves skin healing and induces changes in proteoglycan expression and glycosaminoglycan structure

Elodie Henriet,Sibylle Jäger,Christian Tran,Philippe Bastien,Jean-François Michelet,Anne-Marie Minondo,Florian Formanek,Maria Dalko-Csiba,Hugues Lortat-Jacob,Lionel Breton,Romain R. Vivès

Biochimica et Biophysica Acta (BBA) - General Subjects（2017）

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摘要

•Jasmonate derivative JAD affects synthesis of proteoglycans and glycosaminoglycans.•JAD promotes FGF-7 activity.•JAD improves skin healing in vivo.•A novel mechanism for jasmonate biological activities in mammals is proposed.

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关键词

CS,DEJ,DS,ECM,FGF,GAG,HA,GalNAc,GlcNAc,HexUA,JAD,PG,pHEK,RPIP,RT,SDC,TEM

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