Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Nathan D. Grubaugh,Jason T. Ladner,Moritz U. G. Kraemer,Gytis Dudas,Amanda L. Tan,Karthik Gangavarapu,Michael R. Wiley,Stephen White,Julien Thézé,Diogo M. Magnani,Karla Prieto,Daniel Reyes,Andrea M. Bingham,Lauren M. Paul,Refugio Robles-Sikisaka,Glenn Oliveira,Darryl Pronty,Carolyn M. Barcellona,Hayden C. Metsky,Mary Lynn Baniecki,Kayla G. Barnes,Bridget Chak,Catherine A. Freije,Adrianne Gladden-Young,Andreas Gnirke, Cynthia Luo,Bronwyn MacInnis,Christian B. Matranga,Daniel J. Park,James Qu,Stephen F. Schaffner,Christopher Tomkins-Tinch, Kendra L. West,Sarah M. Winnicki,Shirlee Wohl,Nathan L. Yozwiak,Joshua Quick,Joseph R. Fauver,Kamran Khan, Shannon E. Brent,Robert C. Reiner Jr,Paola N. Lichtenberger,Michael J. Ricciardi,Varian K. Bailey,David I. Watkins,Marshall R. Cone, Edgar W. Kopp IV, Kelly N. Hogan, Andrew C. Cannons, Reynald Jean,Andrew J. Monaghan,Robert F. Garry,Nicholas J. Loman,Nuno R. Faria, Mario C. Porcelli,Chalmers Vasquez,Elyse R. Nagle,Derek A. T. Cummings,Danielle Stanek,Andrew Rambaut,Mariano Sanchez-Lockhart,Pardis C. Sabeti,Leah D. Gillis,Scott F. Michael,Trevor Bedford,Oliver G. Pybus,Sharon Isern,Gustavo Palacios,Kristian G. Andersen

NATURE（2017）

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摘要

Genome sequencing of Zika virus samples from infected patients and Aedes aegypti mosquitoes in Florida shows that the virus was probably introduced into the United States on multiple occasions, and that the Caribbean is the most likely source.

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关键词

Viral epidemiology,Viral genetics,Science,Humanities and Social Sciences,multidisciplinary

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