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Solubility of amiodarone hydrochloride in aqueous co-solvent mixtures revisited: IBKI preferential solvation analysis

Jian Wang,Anli Xu,Zhiyuan Ma

The Journal of Chemical Thermodynamics（2017）

Cited 12|Views3
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Abstract
•Preferential solvation of AMDH in three co-solvent mixtures was discussed.•Preferential solvation parameters were derived by IKBI method.•AMDH was preferentially solvated by co-solvent in intermediate composition.•Preferential solvation in ethanol system is different from that in the other systems.
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Key words
Amiodarone hydrochloride,Inverse Kirkwood–Buff integrals,IKBI,Preferential solvation
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