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Efficacy and safety of the non-steroidal farnesoid X receptor agonist PX-104 in patients with non-alcoholic fatty liver disease (NAFLD)

Stefan Traussnigg,Christian Kienbacher,Emina Halilbasic,Christian Rechling,Harald Hofer,Petra E. Steindl-Munda,Ghazaleh Gouya,Michael Wolzt,Martin Hornberger,Manfred Birkel,Claus Kremoser,Michael H. Trauner

Zeitschrift Fur Gastroenterologie（2016）

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Abstract
Px-104 is an orally available, non-steroidal agonist of the farnesoid X receptor (FXR) as key regulator of bile acid, glucose and lipid homeostasis. This was the first clinical study with Px-104 in NAFLD patients.
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Drug Efflux Pumps
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