Label-Free Detection Of Nucleic Acid Composition Within Dna Strands Using Surface-Enhanced Raman Spectroscopy

Lindsay M. Freeman,Lin Pang,Yeshaiahu Fainman

2017 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO)（2017）

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摘要

We demonstrate label-free detection of the composition of a single strand of DNA using surface-enhanced Raman spectroscopy in which DNA is linearized to plasmonic surfaces and hundreds of Raman spectra are acquired and statistically analyzed.

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关键词

DNA single strands,label-free nucleic acid detection,plasmonic surfaces,surface-enhanced Raman spectroscopy,Raman spectra

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