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The significance of estradiol metabolites in human corpus luteum physiology

Luigi Devoto,Soledad Henríquez,Paulina Kohen,Jerome F. Strauss

Steroids（2017）

Cited 46|Views12
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Abstract
•2-ME2 plays a role in luteolysis, 4-OHE1 and 16ketoE2 increase angiogenesis in the development of CL.•In a conception cycle, hCG rescues the CL by increasing angiogenesis and diminishes apoptosis.
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Key words
Estrogen metabolites,Corpus luteum,2-Methoxyestradiol,4-Hydroxyestrone,16-Ketoestradiol
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