Molecular cloning and characterization of DNGR-1 in rhesus macaques
Molecular Immunology（2017）
Abstract
•Rhesus macaque DNGR-1 was cloned and has 94.9% sequence identity to that of humans.•Rhesus macaque DNGR-1 could bind dead/damaged cells of both human and rhesus origin.•Rhesus macaque DNGR-1 could recognize cells undergoing pyroptosis.•Rhesus macaque DNGR-1 mRNA was ubiquitous and most abundant in lymphoid tissues.
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Key words
DNGR-1,CLEC9A,Rhesus macaque,Apoptotic cell,Dead cell,Pyroptotic cell,Target
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