Evaluation of the Patients With Internal Carotid Artery Occlusion By ESSEN Score (P2.271)

OBJECTIVE u0026 BACKGROUND: The aim of this study was to evaluate the correlation between ESSEN score and concomitant cerebrovascular diseases in ICAO patients, which may provide evidence for the prediction of risk for recurrent cerebral stroke with ESSEN score and findings from angiography in case of CT. DESIGN/METHODS: A total of 100 ICAO patients who received CTA of the head and neck from 2005 to 2012 were retrospectively reviewed and clinical information was collected. The biochemical findings, site of ICAO in CTA, lesions of contralteral internal carotid artery, concomitant lesions of vertebrobasilar artery and concomitant lesions of other intracranial major arteries were recorded. On the basis of ESSEN score, patients were divided into 2 groups: ESSEN 蠅3 patients and ESSENu003c3 patients. The clinical biochemical findings and concomitant lesions of vertebrobasilar artery and/or other intracranial major arteries were compared between two groups. RESULTS: The plasma homocysteine level in ESSEN 蠅3 patients was significantly higher than that in ESSEN u003c3 patients (Pu003c0.05). ESSEN 蠅3 patients were more likely to develop concomitant lesions of the vertebrobasilar artery (61.67[percnt] vs 40.00[percnt], Pu003c0.05); the number of lesions of intracranial major arteries in ESSEN 蠅3 patients was larger than that in u003c3 points group (Pu003c0.05); the number of affected intracranial major arteries (2 or more arteries) in ESSEN 蠅3 patients was larger than that in ESSENu003c3 patients (67.80[percnt] vs 39.47[percnt], Pu003c0.01). CONCLUSIONS: Patients with ESSEN 蠅3 were more likely to develop hyperhomocysteinemia and have concomitant lesions of vertebrobasilar artery and lesions of 2 or more intracranial major arteries. Our findings may be helpful for the early prevention, diagnosis and therapy of ICAO. Study Supported by: This project was funded by the National Natural Science Foundation of China, No. 81371355; and Beijing Municipal Health System High-Level Technician Cultivation Project, No. 2009-3-07. Disclosure: Dr. Zhang has nothing to disclose. Dr. Lv has nothing to disclose. Dr. Han has nothing to disclose. Dr. Li has nothing to disclose.