Prognostic Factors of Weight Loss After Sleeve Gastrectomy: Multicenter Study in Spain and Portugal

Abstract Introduction Sleeve gastrectomy (SG) has become a technique in its own right although a selective or global indication remains controversial. The weight loss data at 5 years are heterogeneous. The aim of the study is to identify possible prognostic factors of insufficient weight loss after SG. Methods A SG retrospective multicenter study of more than one year follow-up was performed. Failure is considered if EWL u003e50%. Univariate and multivariate study of Cox regression were performed to identify prognostic factors of failure of weight loss at 1, 2 and 3 years of follow up. Results A total of 1565 patients treated in 29 hospitals are included. PSP per year: 70.58 ± 24.7; 3 years 69.39 ± 29.2; 5 years 68.46 ± 23.1. Patients with EWL 50 kg/m 2 , age u003e50 years, DM2, hypertension, OSA, heart disease, multiple comorbidities, distance to pylorus u003e4 cm, bougie u003e40F, treatment with antiplatelet agents. The reinforcement of the suture improved results. In multivariate study DM2 and BMI are independent factors of failure. Conclusion The SG associates a satisfactory weight loss in 79% of patients in the first 5 years; however, some variables such as BMI u003e50, age u003e50, the presence of several comorbidities, more than 5 cm section of the pylorus or bougie u003e40F can increase the risk of weight loss failure.