Observations on the relationship between anisometropia, amblyopia and strabismus

•Hyperopic anisometropia produces amblyopia and increases the severity of strabismic amblyopia.•Form deprivation, regardless of the severity, typically produces axial myopia.•Neither functional nor organic amblyopia consistently produces hyperopia.•Amblyopic eyes can exhibit emmetropizing responses.•Imposed strabismus interferes with emmetropization and produces anisometropia.