Role of miR-15a/miR-16-1 and the TP53 axis in regulating telomerase expression in chronic lymphocytic leukemia
HAEMATOLOGICA(2017)
摘要
Chronic lymphocytic leukemia (CLL), the most prevalent form of leukemia in adults in the western world, has a highly heterogeneous clinical course, and is characterized by genomic instability which gives rise to several chromosomal alterations detectable in more than 80% of CLL cases.[1][1] While
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