Mp86-02 prevalence of frailty among urological cancer patients in comparison with community-dwelling population

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Quality of Life and Shared Decision Making V1 Apr 2017MP86-02 PREVALENCE OF FRAILTY AMONG UROLOGICAL CANCER PATIENTS IN COMPARISON WITH COMMUNITY-DWELLING POPULATION Shingo Hatakeyama, Osamu Soma, Takuma Narita, Kazuhisa Tanaka, Toshikazu Tanaka, Daisuke Noro, Masaaki Oikawa, Yoshimi Tanaka, Teppei Matsumoto, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, and Chikara Ohyama Shingo HatakeyamaShingo Hatakeyama More articles by this author , Osamu SomaOsamu Soma More articles by this author , Takuma NaritaTakuma Narita More articles by this author , Kazuhisa TanakaKazuhisa Tanaka More articles by this author , Toshikazu TanakaToshikazu Tanaka More articles by this author , Daisuke NoroDaisuke Noro More articles by this author , Masaaki OikawaMasaaki Oikawa More articles by this author , Yoshimi TanakaYoshimi Tanaka More articles by this author , Teppei MatsumotoTeppei Matsumoto More articles by this author , Takahiro YoneyamaTakahiro Yoneyama More articles by this author , Yasuhiro HashimotoYasuhiro Hashimoto More articles by this author , Takuya KoieTakuya Koie More articles by this author , and Chikara OhyamaChikara Ohyama More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2685AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The prevalence of frailty is expected to increase due to the worldwide ageing. However, little is known about the prevalence of frailty in urological cancer patients. The aim of this study is to investigate the useful frailty assessment tools for urological cancer patients in comparison with community-dwelling population. METHODS From August 2013 to March 2016, we evaluated 486 consecutive urological cancer patients in our hospital. Urological cancers included prostate cancer (PC, n=226), bladder cancer (BC, n=132), upper tract urothelial carcinoma (UTUC, n=42), and renal cell carcinoma (RCC, n=86). We retrospectively compared age and sex adjusted urological cancer patients and 2766 community-dwelling subjects who underwent frailty assessment including physical status (handgrip strength and gait speed), serum test (serum albumin and renal function), and mental status (exhaustion and depression). Gait speed was evaluated by timed get up and go test (TGUG). Independent factors that were significantly associated with tumor-bearing status were evaluated by multivariate regression analysis. RESULTS The number of pair-matched patients in PC, BC, UTUC, and RCC were 212, 130, 41, and 84. TGUG, handgrip strength, and serum albumin were significantly worse in all types of cancers than controls. Renal function was significantly better in PC, whereas it was worse in BC, UTUC, and RCC than controls. The number of patients with exhaustion or depression were significantly higher in PC. Multivariate regression analysis showed TGUG and serum albumin were significantly associated with tumor-bearing status. CONCLUSIONS Urological cancer patients were significantly frail compared with community-dwelling older adults. Our results provide a picture of the prevalence of frailty in urological patients. TGUG and serum albumin may be simple and useful tools for frailty assessment in urological cancer patients. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1156-e1157 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Shingo Hatakeyama More articles by this author Osamu Soma More articles by this author Takuma Narita More articles by this author Kazuhisa Tanaka More articles by this author Toshikazu Tanaka More articles by this author Daisuke Noro More articles by this author Masaaki Oikawa More articles by this author Yoshimi Tanaka More articles by this author Teppei Matsumoto More articles by this author Takahiro Yoneyama More articles by this author Yasuhiro Hashimoto More articles by this author Takuya Koie More articles by this author Chikara Ohyama More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...