Pd66-12 outcomes on ileal mucosal cuff management during radical nephroureterectomy

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy VI1 Apr 2017PD66-12 OUTCOMES ON ILEAL MUCOSAL CUFF MANAGEMENT DURING RADICAL NEPHROURETERECTOMY Amir Toussi, Vidit Sharma, Tanner Miest, George Chow, Bradley Leibovich, and Matthew Tollefson Amir ToussiAmir Toussi More articles by this author , Vidit SharmaVidit Sharma More articles by this author , Tanner MiestTanner Miest More articles by this author , George ChowGeorge Chow More articles by this author , Bradley LeibovichBradley Leibovich More articles by this author , and Matthew TollefsonMatthew Tollefson More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2975AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Patients who undergo radical cystectomy for urothelial cancer are at risk for upper tract urothelial carcinoma (UTUC). It is well-accepted that the removal of a formal bladder cuff at the time of radical nephroureterectomy (RNU) results in improved oncologic outcomes. However, the effects of ileal mucosal cuff excision in patients undergoing RNU who have had a prior urinary diversion has not been studied. To our knowledge, we present the first report on outcomes of ileal mucosal cuff management for patients undergoing RNU for UTUC. METHODS Between 1995 and 2009 we retrospectively reviewed 483 patients at Mayo Clinic who underwent RNU for primary UTUC. We identified 41 patients who underwent RNU after having a previous radical cystectomy. Patients with mucosal cuff excision identified pathologically were analyzed and compared to those without a mucosal cuff. Kaplan Meier analyses were used to estimate recurrence free survival. RESULTS Median age of the cohort was 72 (IQR 66, 77) and 32 (78%) were male. A total of 18 (43.9%) patients underwent ileal cuff excision. Tumor multifocality, non-muscle invasive tumors (