Statin use and risk of lung cancer in males: A case-control study in Taiwan

Objectives: To explore the association between statin use and lung cancer risk in men in Taiwan Design: A nested case-control study Setting: Data from the Taiwan National Health Insurance Program, 2000 to 2010 Subjects: Two thousand two hundred and ninety male patients aged 20 years or older with newly diagnosed lung cancer as cases and 9160 male subjects without lung cancer as controls Main Outcome Measure: The association between statin use and lung cancer risk was estimated Results: After adjustment for confounders including pulmonary tuberculosis, chronic obstructive pulmonary disease, asbestosis and tobacco use, multivariate logistic regression showed the adjusted odds ratio of lung cancer was 0.79 for the statins-use group (95% CI: 0.68, 0.91), when compared with no use of statins. Conclusions: We found an association between statin use and lung cancer risk in men in Taiwan.