Clinical comparison of noninvasive urine tests for ruling out recurrent urothelial carcinoma

Yair Lotan,Paul OʼSullivan,Jay D. Raman,Sharokh F. Shariat, Laimonis Kavalieris,Chris Frampton,Parry Guilford, Carthika Luxmanan,James Suttie,Henry Crist,Douglas Scherr, Scott Asroff,Evan Goldfischer, Jeffrey Thill,David Darling

Urologic Oncology: Seminars and Original Investigations（2017）

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摘要

•Cxbladder Monitor is a molecular diagnostic test for ruling out recurrent bladder cancer.•Test performance was compared with FDA-approved, noninvasive monitoring tests.•Cxbladder Monitor outperformed urine cytology and NMP22 Bladderchek/ELISA.•Cxbladder Monitor also outperformed UroVysion FISH in an exploratory analysis.•Utility is in confirming a negative cystoscopy or directly ruling out recurrent UC.

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关键词

Urinary bladder neoplasms,Urologic neoplasms,Diagnostic techniques,Urological,Molecular diagnostic techniques,Biomarkers

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